Cone-rod dystrophy

Researchers find causative factors in retinal dystrophies

Scientists from the Florida campus of The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision. Their research helps explain why mutations in the gene encoding α2δ4 lead to retinal dystrophy, a disease characterized by defective color vision and night blindness. To study how this protein supports vision, the researchers modeled

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Regenerating_mouse retinal ganglion cell

Visual Activity Regenerates Neural Connections Between Eye and Brain

A study in mice shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS)

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Hydroxychloroquine toxicity

Hydroxychloroquine screening lacks adherence to recommended guidelines

Of patients presenting for hydroxychloroquine screening at a large multispecialty ophthalmic practice, almost half of the patients on hydroxychoroquine did not receive appropriate evaluation, indicating lack of adherence to guidelines. Spectral-domain optical coherence tomography (SD OCT) and 10-2 Humphrey visual field (HVF) were found to be the preferred screening modalities, with others being fundus autofluorescence (FAF)

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