Diabetic Retinopathy

Researchers identify new target for abnormal blood vessel growth in the eyes

A team led by Massachusetts Eye and Ear researchers has identified a novel therapeutic target for retinal neovascularization, or abnormal blood vessel growth in the retina, a hallmark of advanced diabetic eye disease. According to a report published online in Diabetes, the transcription factor RUNX1 was found in abnormal retinal blood vessels, and by inhibiting

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Cone-rod dystrophy

Researchers find causative factors in retinal dystrophies

Scientists from the Florida campus of The Scripps Research Institute have discovered how a protein called α2δ4 establishes proper vision. Their research helps explain why mutations in the gene encoding α2δ4 lead to retinal dystrophy, a disease characterized by defective color vision and night blindness. To study how this protein supports vision, the researchers modeled

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(c) Ophthotech

Ophthotech Announces Results from Pivotal Phase 3 Trials of Fovista ® in Wet AMD

Ophthotech Corporation has announced that the pre-specified primary endpoint of mean change in visual acuity at 12 months was not achieved in its two pivotal Phase 3 clinical trials investigating superiority of Fovista (pegpleranib) anti-PDGF therapy in combination with Lucentis (ranibizumab) anti-VEGF therapy compared to Lucentis monotherapy for the treatment of wet age-related macular degeneration

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Port-au-Prince, Haiti – July 5-8, 2016

Alice Y. Kim was the Outreach Manager of Retina Global until recently, and she is currently on her way to a residency in ophthalmology. She graduated from the Keck School of Medicine of the University of Southern California (Los Angeles, California, USA). She plans to pursue a career in ophthalmology, while contributing to the scientific and

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Regenerating_mouse retinal ganglion cell

Visual Activity Regenerates Neural Connections Between Eye and Brain

A study in mice shows for the first time that high-contrast visual stimulation can help damaged retinal neurons regrow retinal ganglion cell axons. In combination with chemically induced neural stimulation, axons grew further than in strategies tried previously. Treated mice partially regained visual function. The study also demonstrates that adult regenerated central nervous system (CNS)

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Macular edema on OCT

Eylea outperforms Avastin for DME in patients with moderate vision loss

A two-year clinical trial that compared three drugs for diabetic macular edema (DME) found that visual improvement was greater for participants receiving the drug Eylea (aflibercept) than for those receiving Avastin (bevacizumab), but only among participants starting treatment with 20/50 or worse vision.  Gains after two years were about the same for Eylea and Lucentis

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Surgery in monkey eye

Stem-cell derived retina found to improve vision in monkeys with RP

Researchers at the RIKEN Institute in Japan have succeeded in growing human embryonic stem cell-derived retina (hESC-retina) and transplanting that tissue into the retinas of rhesus monkeys with Retinitis Pigmentosa (RP). Three weeks after the treatment, visual tests on two of the monkeys found their vision had improved. In the study, published in the journal PNAS,

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Laser gene delivery system

A gene therapy platform for macular degeneration patients

Physics researchers at The University of Texas at Arlington have developed a new platform that uses ultrafast near-infrared lasers to deliver gene therapy to damaged areas of the retina to enable vision restoration in patients with photo-degenerative diseases such as macular degeneration. Samarenda Mohanty, assistant professor of physics and head of UTA’s Biophysics and Physiology

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